Pharmacological Therapy for Obesity Patients

Obesity is associated with various health problems including cardiovascular disease, diabetes, gallstones, and osteoarthritis. Depression, other psychosocial problems, and some medications are factors that can exacerbate obesity. The main therapy for obesity is an appropriate diet, the patient is given a clear explanation of how to diet and provides maximum support, and is advised to increase physical activity.

Quitting smoking (while still not losing weight) can be beneficial before trying a weight loss program because smoking can be more dangerous than obesity. Joining a group can help a patient a lot.

Severe obesity should be treated in a weight loss center with trained staff. Patients should receive advice on diet and lifestyle modifications and should be monitored for all changes in weight, blood pressure, and other associated conditions.

Anti-obesity drugs should only be given to individuals who have a body mass index (BMI) of 30 kg/m2 or more (BMI or Body Mass Index is a person’s weight divided by the square of their height in m2) who, after at least 3 months of following a diet, modify their behavior. and exercise, but fail to achieve reasonable weight loss. If there are risk factors (such as diabetes mellitus, coronary heart disease, hypertension, and obstructive sleep apnea), this drug is appropriate to be prescribed even if the individual has a BMI of 27 kg/m2. Medication should not be used as the sole element of treating obesity. Patients should be monitored regularly, treatment should be discontinued if weight loss is less than 5% after the first 12 weeks or the patient gains weight again during treatment.

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Use of Xenical for Obese Patients

Xenical is a drug used for weight loss in people who are overweight or obese. This drug can also reduce the risk of gaining weight again. To be more effective, the consumption of this drug must be accompanied by regular exercise and diet to limit calorie intake.

Xenical is an anti-obesity drug that works by inhibiting fat-breaking enzymes, so fat cannot be digested and absorbed by the body. That way, the fat consumed will be removed and the weight is expected to be reduced. Xenical should only be used as prescribed by a doctor.

Being overweight and obese do have many negative effects on health. In addition to increasing the risk of diabetes, obesity can also increase the risk of heart disease. Actually, Xenical has been used since 1999 as an obesity therapy that requires a doctor’s prescription. However, with the consideration of these health aspects, the Food and Drug Administration (FDA) has now approved the circulation of Xenical capsules as an over-the-counter (OTC) drug. Of course with a lower dose than those commonly prescribed by doctors (Xenical 120 mg). ).

Over-the-counter Xenical is in a dose of 60 mg, used in obese patients aged > 18 years with reduced calories, strict diets, and special exercise programs. The capsules can be taken up to 3 times a day before, while up to an hour after eating a 15 g fatty meal (more than 15 grams can cause digestive problems). And given the risk of missing certain nutrients (vitamins A, D, E, K, beta carotene), it is highly recommended to take a multivitamin at least 2 hours before or after taking Xenical, such as at bedtime.

A common side effect is a change in the pattern of small bowel activity, which can manifest as soft or oily watery stools. Consumption of a low-fat diet can reduce the risk of these side effects, but fatigue, liver inflammation, and rectal pain can also be found. Patients with a history of transplantation should also not take Xenical because drug interactions can occur. And patients with certain history such as diabetes, thyroid (goiter) should consult a doctor first before use.

In conclusion, your current body mass index already meets one of the criteria for using Xenical. However, without a diet and exercise program, the effectiveness of Xenical is very small or not effective at all. So it’s clear that Xenical is not a magic pill that instantly melts fat. Its use must still be accompanied by a strict diet and exercise. If after a strict diet, exercise, and consumption of Xenical there is no weight loss, the doctor will suggest obesity surgery.